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Among these four isoforms, AK1C2 and AK1C3 share 87.9% amino acid sequence identity and both enzymes possess 3-hydroxysteroid dehydrogenase (3-HSD) activity and catalyze 5-dihydrotesterone reduction to produce 5-androstane-3,17-diol (3-diol) 30

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491 Inhibiting ferroptosis has a protective effect on obese and diabetic cardiomyopathy

(PubMed) Begin MJ, Ste-Marie LG, Coupal L, Ethier J, Rakel A

[PubMed 3349935] 1155
