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doi: 10.1073/pnas.1811389115CrossRefGoogle ScholarPubMed Pu, J., Liu, Y., Zhang, H., Tian, L., Gui, S., Yu, Y., Xie, P
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NNMT inhibitors are selective and do not impact related methyltransferases or enzymes in the NAD + salvage pathway The selectivity of NNMT inhibitors was confirmed by testing against a panel of structurally similar methyltransferases and two enzymes in the NAD + salvage pathway (NAMPT and SIRT1
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