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Ongoing monitoring ensures safety and efficacy

Science 276:16991702, PMID: 9180080 Takaki J, Fujimori K, Miura M, Suzuki T, Sekino Y, Sato K (2012) l-glutamate released from activated microglia downregulates astrocytic l-glutamate transporter expression in neuroinflammation: the collusion hypothesis for increased extracellular l-glutamate concentration in neuroinflammation

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Although it is plausible that select peptides may enter formal clinical trials under an IND or through fast-track orphan designation pathways, this measured approach allows innovation to move forward without compromising ethics, compliance, or patient safety

A 2-year study of 100 patients with vitiligo, who were treated with oral folic acid (5 mg) and VitB12 (1 mg) in combination with sunlight exposure and UVB radiation, showed re-pigmentation in 52 participants with stable and progressive vitiligo

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