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The head groups of these lipids interact with the Arg55 and Arg67 of MlaD, and also with the Arg196 of MlaE (Fig

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LIP) and COP1-dependent stabilization fine-tune its oncogenic output, as seen in neuro-inflammation-associated malignancies and colorectal cancer [3, 149], where CEBPB-SERPINA1-STAT3 axis activation accelerates tumor growth and metastasis

Two categories of approaches are considered, including fluid membrane (e.g., lipid bilayer) and polymerized membrane (e.g., red blood cell) models