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[DOI] [PMC free article] [PubMed] [Google Scholar] [149].Moussa EM, Panchal JP, Moorthy BS, Blum JS, Joubert MK, Narhi LO, Topp EM, Immunogenicity of Therapeutic Protein Aggregates, Journal of Pharmaceutical Sciences, 105 (2016) 417430

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Decreased Level of Sirt1 in AKI NAD + depletion also caused the inhibition of Sirt1 and its downstream target genes, which mediates mitochondrial quality control and renal tubular ATP production level