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Some symptoms of a vitamin B12 deficiency include: difficulty thinking brain fog fatigue pale skin weight loss dementia numbness and tingling in hands and feet mood changes decreased appetite constipation A lack of animal protein and following a plant-based diet sans appropriate supplementation can lead to a vitamin B12 deficiency

You have to consume food and drinks that have vitamin B12 to get it

Wu and Xie, 2025

The anti-estrogenic activity of indole-3-carbinol in neonatal rat osteoblasts is associated with the estrogen receptor antagonist 2-hydroxyestradiol

It makes the experience much smoother and, as a bonus, the Vitamin C in citrus actually helps boost glutathione absorption significantly

Most of what we know is preclinical, and real-world human trials are not yet strong