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However, excessive mechanical stress and impingement can upregulate MMP expression, leading to increased collagen degradation and weakening of the ACL

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Start with the lowest dose and increase gradually as tolerated

doi: 10.1016/j.heliyon.2024.e24586 [DOI] [PMC free article] [PubMed] [Google Scholar] 189.Zong Y, Yu W, Hong H, et al

D'Alessandro A, Fu X, Reisz JA, Kanias T, Page GP, Stone M, Kleinman S, Zimring JC, Busch M

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