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Description
Hara et al., 2017

10.1021/acs.biochem.7b00669 Biochemistry 29 HeefnerD
Reward and relapse: complete gene-induced dissociation in an animal model of alcohol dependence

Pharmacodynamics: The observed pharmacodynamic effects in animal models often outlast measurable systemic exposure, suggesting mechanisms that include local tissue modulation, induction of growthfactor expression, and initiation of reparative cascades rather than sustained receptor occupancy requiring prolonged systemic presence

Exchange of cystine and glutamate across plasma membrane of human fibroblasts

A.SinyovV
