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Axonal Transport Deficits and Neurodegenerative Diseases

These systems can simultaneously act as gene carriers and therapeutic agents

smegmatis missense mutation that conferred co-resistance to both INH and Ethionamide (ETH) (129)

( B ) Representative images of H2AX foci (red) and DAPI nuclear staining (blue) in LLC and H460 cells treated as indicated

Virus Res 2013;176:137-143

Low GSH in aging is associated with lower intake of GSH precursors, mainly cysteine, and lower GSH synthesis evidencing diminished function of nuclear factor erythroid 2related factor 2 (Nrf2)-dependent inductive mechanisms that enhance glutamate cysteine ligase expression, rate limiting factor for the synthesis of GSH (McCarty and DiNicolantonio, 2015)