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The accumulation of senescent cells creates an immunosuppressive environment, promoting viral replication and transmission and thereby accelerating the progression of HIV disease

This conclusion has been confirmed by showing that cytosolic expression of GSH synthase rescues the seedling lethal gsh2 mutant (Pasternak et al., 2008)

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Aging and osteoarthritis: the role of chondrocyte senescence and aging changes in the cartilage matrix

PLoS ONE 9 , e105262 (2014)