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A full understanding of the operation of this pathway could help to design molecularly targeted therapeutics aimed at preventing muscle wasting, which occurs in a variety of pathologic contexts and in the course of aging.

This study aimed to identify potential activators of GPx4, an essential inhibitor to ferroptosis, as a novel neuroprotective strategy in MS treatment

Inflammaging is a typical pathological inflammatory state associated with immunosenescence and is characterized by excessive expression of proinflammatory cytokines in aged immune cells