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doi: 10.1016/j.preteyeres.2007.10.001

The MVA pathway has been regarded as a vital mechanism of selenoprotein synthesis

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Participants were mostly male aged 330 years old
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The cultured SGN explants from WT or gpx1 / mice were exposed to peroxynitrite with or without ebselen pretreatment, and the expression changes of 4-HNE were examined to evaluate the oxidative stress level in SGNs (Figure 5A)
