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Moreover, DOX upregulated GPX4 as well as FTH1 in H9c2 cells (Zhang et al., 2021

[DOI] [PubMed] [Google Scholar] Bacci M, Lorito N, Ippolito L

Obesity, kidney dysfunction and hypertension: mechanistic links

Exposure to GOx triggered tumor starvation and produced H2O2 to provide reactants for the MOF-mediated Fenton reaction to produce large amounts of ROS, whilst releasing curcumin to induce the autophagic death of tumor cells (18)

Encapsulation of curcumin in alginate-chitosan-pluronic composite nanoparticles for delivery to cancer cells

This work was supported by the National Institutes of Health (R43NS112050 and R44NS130776-01 to APM) and the National Science Foundation (1548490 and 1660165 to SH)
