a melanotic macule Oral pathology: Noting pigmented that often presents a diagnostic dilemma a Melanotic macule at the

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[DOI] [PMC free article] [PubMed] [Google Scholar] 93.Higuchi-Sanabria R., Paul J.W., 3rd, Durieux J., Benitez C., Frankino P.A., Tronnes S.U., Garcia G., Daniele J.R., Monshietehadi S., Dillin A

Melanotan 2 peptide is a synthetic hormone analogue that stimulates melanin production in the skin, leading to a darker complexion resembling a tan

This in vitro cell culture study demonstrated receptor activation through the cAMP signaling pathway, which is a key second messenger system in G-protein coupled receptor signaling

Pinhasov A, Mandel S, Torchinsky A, Giladi E, Pittel Z, Goldsweig AM, et al

In this context, lipid droplets (LDs), intracellular organelles involved in lipid storage, signaling, and energy homeostasis, have emerged as key regulators of cellular stress responses, including inflammation and oxidative stress, particularly in neural and endothelial cells (Zhang et al., 2025)