glutathione-protein mixed disulfide Modification of proteins by glutathionylation. This reversible Protein Disulfide Bond Formation in

Known anti-persister strategies As many studies have found increased ROS levels and altered antioxidant pathways in melanoma persisters, several strategies have been developed using these characteristics as targets (Table 1)

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3 Disulfidptosis-related programmed cell death There are currently many types of cell death, such as pyroptosis, apoptosis, and autophagy, but only ferroptosis and cuproptosis are related to disulfidptosis

Further studies focused on new effector cell subsets, novel antibodies and ADC, besides those listed in Table 3 , and combination of drugs with immunotherapeutic tools may open new avenues to fight this tumor

[DOI] [PubMed] [Google Scholar] 78.Agathos E., Tentolouris A., Eleftheriadou I., Katsaouni P., Nemtzas I., Petrou A., Papanikolaou C., Tentolouris N

P., Olpin, S