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To clarify this mechanism of amplification, we propose the notion of pathological transmitter-immunity cycle (Fig

doi: 10.1016/j.biortech.2010.03.072

Using pharmacological approaches, we demonstrate that VRK2-deficient pancreatic cancer (PC) cells exhibit heightened vulnerability to glutathione (GSH) metabolic pathway inhibition
10.1002/ana.10483

Both of the compounds however, can be excreted from the cells

A common mechanism for preventing irreversible oxidation of catalytic cysteines is to incorporate the SO intermediate into a disulfide (SS) bond or sulfenicamide (SN) bond
