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Describe how the pentose phosphate pathway and the process of DNA replication interface with the biosynthesis of purine and pyrimidine nucleotides

Functionally, MCS represents an adaptive attempt to preserve core cell functionsincluding proliferation, differentiation, migration, secretion, neuronal signaling, and muscle contractionand, under pathological conditions, to sustain pro-inflammatory activity [187,190]

Colman RJ, Anderson RM, Johnson SC, Kastman EK, Kosmatka KJ, Beasley TM, Allison DB, Cruzen C, Simmons HA, Kemnitz JW, Weindruch R (2009) Caloric restriction delays disease onset and mortality in rhesus monkeys

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Nature 268:654655 Norenberg MD, Martinez-Hernandez A (1979) Fine structural localization of glutamine synthetase in astrocytes of rat brain

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