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References 1 Peng, M., et al

Clinical trials have demonstrated curcumin's efficacy in reducing the severity of chronic symptoms

The Nrf2/HO-1 pathway plays a vital role in antioxidative and iron-homeostatic responses, exhibiting a well-documented double-edged sword effect in ferroptosis regulation

An in vivo study on a high fat diet enriched with glutamine administered to Wistar rats found that glucose uptake increased with stimulation of insulin signaling in skeletal muscles and reduced hepatic gluconeogenesis, which both showed improvement in insulin sensitivity [43]

Indeed, thyroxine treatment of animals with heterozygous expression of misfolded mutant TG does not appreciably lower ER stress markers in the thyroid gland but completely inhibits thyroid cell death (31)

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