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FIGURE 6 Fumaric Acid Does Not Activate Th1 and Th17 Cells in vitro Earlier studies have shown that succinic acid does not affect CD4 + T cell activation in vitro, although it can promote the proliferation and activation of CD4 + T cells in vitro following antigen presentation by dendritic cells (Rubic et al., 2008)

Beyotime, Shanghai, China) and live/dead cells (BB4126

Cell 79:583593 Liao H, Fang Y, Yin J, He M, Wei Y, Zhang J, Yong S, Cha J, Song L, Zhu X, Chen X, Kov J, Hou Q, Ma Z, Zhou X et al (2025) Rice transcription factor bHLH25 confers resistance to multiple diseases by sensing H 2 O 2

doi:10.1371/journal.pone.0170748 85

Gymnemic acids have antidiabetic, anti-sweetener, and anti-inflammatory activities

Caffeine (but judiciously): if you feel like you need a pick me up, caffeine can help
