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Interspecific variation in one-carbon metabolism within the ovarian follicle, oocyte, and preimplantation embryo: consequences for epigenetic programming of DNA methylation

More than 40% of marketed drugs are metabolized by the CYP3A4 isoform, but other members of the CYPs family are involved as well, such as CYP2C8, CYP2C9, and CYP2D6 [13]

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10.1186/s13059-014-0550-8 74 LuettichK.SharmaM.YepiskoposyanH.BrehenyD.LoweF

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Although the mechanism of action of auranofin is incompletely understood, some reports link it to altered regulation of p53 pathways