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In studies of human glioblastoma, the absence of exogenous Gln significantly reduces glutamate levels, resulting in the conversion of the dimer GLS1 into a self-assembled, extremely low Km filamentous polymer that further depletes intracellular Gln

Contrarily, BPC 157 therapy counteracted the damaging effect of systemic administration of high doses of capsaicin (milligrams per kilogram range, long-lasting damage of somatosensory neurons, more when given in newborn animals)

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Inestrosa, Neurodevelopmental impact of the offspring by thyroid hormone system-disrupting environmental chemicals during pregnancy

[DOI] [PubMed] [Google Scholar] 6.Samuele A., Mangiagalli A., Armentero M.-T., Fancellu R., Bazzini E., Vairetti M., Ferrigno A., Richelmi P., Nappi G., Blandini F

a combination of 1mM IBMX, 1 M dexamethasone, and 10 g/ml of insulin in media were added to fully confluent 3T3-L1 fibroblasts for three days (days 03) to initiate differentiation
