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The main feature of NAFLD is the FA accumulation in liver parenchyma, due to an enhancement in FA uptake from plasma, in addition to an overstimulation of the de novo lipogenesis via SREBP-1c transcription factor activation [83]
These investigations require an interdisciplinary approach, integrating knowledge and methodologies from chemistry, materials science, biology, and clinical medicine
It is the precursor to the amino acid cysteine and the pervasive methylation agent rSAM
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10.1093/ndt/gfu233 [DOI] [PubMed] [Google Scholar] Khatami P
The BAX/Bcl2 ratio increased 8-fold
