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Metabolic imaging of energy metabolism in traumatic brain injury using hyperpolarized [1-13C]pyruvate
The BK channel opener BMS-191011 was shown to suppress behavioral evidence of salicylate-induced tinnitus in mice, with local application in the inferior colliculus reversing salicylate-suppressed spontaneous activity, particularly in the frequency region corresponding to the tinnitus percept, highlighting a key site of action see in Figure 2 - (Scott et al., 2022)