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Therefore, Nrf2 is identified as an important ferroptosis regulator and an attractive pharmacological target in DKD

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For example, under physiological circumstances, the protein transferrin cannot enter the brain from the blood due to the blood-brain barrier and the blood-cerebrospinal barrier [254,255]

Van Gool F, Galli M, Gueydan C, Kruys V, Prevot PP, Bedalov A, et al