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The mechanisms are different and do not directly conflict, but absence of conflict is not the same as evidence of benefit

& Matusiewicz, M

In patients with mild cognitive impairment (often a precursor to Alzheimers disease), prolonged melatonin supplementation reportedly slowed the progression of cognitive decline and improved sleep and mood, though larger trials are needed

Diagnosis of deep endometriosis by clinical examination during menstruation and plasma CA-125 concentration

Performance in the forced swim task (a model of depression) was improved in male rats, but a more severe depression-like behavior was reported in female rats

doi: 10.1016/j.freeradbiomed.2005.09.038