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Earlier in vitro studies showed that these CE-rich particles effectively cholesterol load VSMCs (151,152)

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In contrast, an acute loading test in two patients found that coffee did not modify the pharmacokinetics of LT4 [78]

And GLP-1 peptide drugs like semaglutide (Ozempic and Wegovy) and tirzepatide (Mounjaro and Zepbound) have undergone extensive testing in clinical trials to become FDA-approved drugs for obesity and type 2 diabetes

Together they cover gut lining repair, inflammation control and immune defence at the gut level