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van Leeuwen R, Boekhoorn S, Vingerling JR, Witteman JC, Klaver CC, Hofman A, et al

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showed that Hif-2 deficiency in mice enhances bone mass, partially because HIF-2 directly induces RANKL expression in osteoblasts leading to increased osteoclastogenesis 8

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Cyclooxygenase inhibitors and the antiplatelet effects of aspirin
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