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Chen and Chiou, 1992)

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How nanoparticles open the paracellular route of biological barriers: mechanisms, applications, and prospects

In particular, during the acute phase, in which HCV replicates at a high rate, a marked oxidative stress due to the NOX4 isoform, ubiquitously expressed in parenchymal and non-parenchymal liver cells, has been observed, as well as a concomitant decrease in GSH

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NaAsO induces cytotoxic ROS and inhibits glycolysis