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Betaine's special thing is being an osmolyte , a molecule that helps to control cell-water balance
[DOI] [PubMed] [Google Scholar] 47.Thornalley PJ
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10.1016/j.jchromb2016.02.015 J Chromatogr B Analyt Technol Biomed Life Sci

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GR levels alone are therefore a fairly good biomarker of dementia. However, the mere presence of the enzyme does not guarantee its high activity