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Studies show that at doses of 10,000 16,000 mg/day, some people will have an odd, fishy odor due to the excretion of trimethylamine

Neurochem Int 40(6):543551 Menzies FM, Cookson MR, Taylor RW, Turnbull DM, Chrzanowska-Lightowlers ZM, Dong L et al (2002b) Mitochondrial dysfunction in a cell culture model of familial amyotrophic lateral sclerosis
Changes in phospholipid ratios can also affect energy production and have been associated with metabolic disorders such as obesity, diabetes and atherosclerosis (van der Veen J, et al., 2017)

For me, taking Vitamin K2 is a lifesaver in the fact that my scans have not shown calcification of blood vessels
Anti-cancer effect of pharmacologic ascorbate and its interaction with supplementary parenteral glutathione in preclinical cancer models
LinDSHuangYWHoCSHungPLHsuMHWangTJet alOxidative insults and mitochondrial DNA mutation promote enhanced autophagy and mitophagy compromising cell viability in pluripotent cell model of mitochondrial disease