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Furthermore, the P62/Keap1/Nrf2 axis also suppresses ferroptosis by inhibiting oxidative stress [45]

thaliana orthologs, some ankyrin repeat proteins have been shown to mediate membrane bound protein-protein interactions that facilitate heavy metal transport in A

Among the remaining metabolites, particularly notable are components of purine metabolism, ribose-5-phosphate, and uric acid, demonstrating approximately 4-fold elevation in POAG

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HHcy can increase total cholesterol, triglycerides, and low-density lipoprotein (LDL) cholesterol, while decreasing high-density lipoprotein (HDL) cholesterol in these mice, accelerating the development and instability of atherosclerotic plaques [45]

The presence of these multiple mechanisms makes it challenging to precisely measure the net effect of zinc and to understand its complex relationship with epilepsy [38]