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Also see Figure 3

Haidari, F., Abiri, B., Haghighizadeh, M

doi: 10.1055/a-1886-5697 170 FigueroaBASaidSAOrdenanaCRezaeiMOrfahliLMDubeGPet al

Too much signal and the doseresponse curve flattens - you spend more money and expose yourself to more side effects for no extra benefit

Drug-resistant tumor cell lines and oxidative stress are associated with increased cell GSH levels, GCL activity, GCLC mRNA levels and GCLC gene transcription [5763]

10.1517/13543780902849244 200 MurakamiK.YoshinoM