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2001;21(4B):2895-2900

A holistic approach is always the most effective way to see lasting changes

Genetic and environmental interplay : mutations in SNCA , LRRK2 , PINK1 , and VPS35 interact with toxins and metabolic stressors to trigger degeneration

Clomipramine hydrochloride should be discontinued before initiating treatment with the MAOI (see CONTRAINDICATIONS and DOSAGE AND ADMINISTRATION)
Overexpression of dFOXO has been shown to protect DA neurons in Drosophila Pink1 -null mutants [161], while other studies have shown that dFOXO-induced apoptosis mediates DA neuron death in Drosophila DJ-1 loss-of-function mutants [162] and dLRRK mutants [163]

Xu K, Liu X, Liu J, Zhang Y, Ding X, Li L, Sun J
