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: 250 mcg ( ), 500 mcg

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Thiol-disulfide balance: From the concept of oxidative stress to that of redox regulation

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However, tunicamycin induces ER stress through a different mechanism, by inhibiting N-linked glycosylation, a critical step in glycoprotein synthesis, leading to the accumulation of misfolded proteins specifically within the ER 46,47

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It has only central analgesic effects mediated by its active metabolite N -arachidonoyl-phenolamine (AM404), which forms in the CNS and acts as an anandamide reuptake inhibitor in the dorsal horn of the spinal cord [24]

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10.1038/srep25777 253 LaudaniS.TorrisiS

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