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found that patients with T2DM, hyperlipidemia, coronary artery disease, polycystic ovary disease (PCOD), or obesity, and on metformin therapy were significantly associated with increased risk of vitamin B 12 deficiency and lower serum vitamin B 12 concentrations [9]

What Causes Vitamin B12 Deficiency in Adults

Using one needle for both caused itch problem

But theres studies now showing that if you are in this sort of stressed state, your brain is stressed like for sleep deprivation, for example, youre sleep deprived for 21 hours and your brains not working very good after not sleeping for 21 hours, right

10.1007/s10620-008-0332-9 130 SkorjanecS.KokotA.DrmicD.RadicB.SeverM.KlicekR.et al (2015)

I'm guessing this has to do with the slight uptick in E2