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Cytokines and Chemokines in Autoimmune Disease: an Overview
62-64 The inhibition of MPO has been studied in a cigarette smoke-induced emphysema model, in guinea pigs
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The inability to maintain reduced glutathione in RBCs leads to increased accumulation of peroxides, predominantly H 2 O 2 , that in turn results in a weakening of the cell wall as a result of membrane lipid peroxidation resulting in concomitant hemolysis
