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The molecular and cellular insight into the toxicology of bortezomib-induced peripheral neuropathy

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In vivo 85% of the accumulated glutamate is converted to glutamine and re-used, whereas the last 15% is oxidatively degraded (Rothman et al., 2011)

The training period was conducted through five consecutive days before the animals underwent surgery

Nevertheless, it is recommended to seek medical attention if side effects persist or worsen

Although the precise mechanism by which these LXR agonists effect a reduction in the progression of atherosclerosis is not clear, it is known that the genes encoding ABCA1 and ABCG1 contain LXR-binding sites