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An increasing number of studies have shown that ubiquitin specific peptidases (USPs), a subtype of deubiquitinases, can affect tumor progression by regulating the stability or biological function of substrate proteins

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This specific mechanism of action makes 5-Amino-1MQ an object of interest for scientific research looking for ways to influence various physiological processes associated with NNMT

Among various cancer cells, HCT116 cells have highest intracellular L-glutathione (GSH) level and SNU478 cells showed the lowest GSH level

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