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They used a tool to apply pressure to the appendages and measured the point at which the murine models pulled their appendages away

Common injection sites include the abdomen (at least 2 inches from the navel), the front of the thighs, and the back of the upper arms (if someone else is administering)

It does not imply any clinical, therapeutic, or consumer application

You can use any amount of water, the dosage per unit just decreases

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Dogs: 1 - 2mL i.m