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The Arabidopsis transcription factor CAMTA3 [also named signal responsive 1 (SR1)] is a negative regulator of plant immunity

Specific ferroptosis inhibitors like Ferrostatin-1 can effectively block lipid peroxidation but suffer from poor metabolic stability in vivo , low bioavailability, and potential off-target effects (112)

doi: 10.1016/j.ijantimicag.2018.03.010 272 SchmidtJ.SmithN

When considered alongside diverse experimental data, these stage-restricted, cultivar-biased signatures support a hypothetical model in which strengthened ASCGSH recycling and thiol-redox hubs sustain H 2 O 2 signaling while limiting oxidative damage

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This effect may result from T-cell hyporesponsiveness induced by continued ROS exposure, which was induced by imbalance between ROS generation and scavenging through inhibition of antioxidant activity of Gpx1