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First, at the DNA methylation level, cytosine methylation, specifically promoter hypermethylation or global hypomethylation, directly modulates gene expression

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IRF7: role and regulation in immunity and autoimmunity
ROS in aging Caenorhabditis elegans: damage or signaling

10.1038/s41392-020-00326-0 43 KitagawaA.JacobC.JordanA.WaddellI.McMurtryI

In the next section, we discuss the role of copper homeostasis in atherosclerosis, stroke, ischemia-reperfusion injury, and heart failure, respectively
