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J.TangL.JiangR.ZhangF

Global statistics show that ~49% of malignant brain tumors are glioblastomas and 30% are diffuse infiltrating low-grade gliomas (1)
The collected media was centrifuged to remove cell debris

Science 311:17641767 Rees JF, de Wergifosse B, Noiset O, Dubuisson M, Janssens B, Thompson EM (1998) The origins of marine bioluminescence: turning oxygen defence mechanisms into deep-sea communication tools

Indeed, since pro-tumoral macrophages require iron to differentiate, iron chelation may sensitize tumors to immune-based therapies

Photosynthetica 41:571578 Le Martret B, Poage M, Shiel K, Nugent GD, Dix PJ (2011) Tobacco chloroplast transformants expressing genes encoding dehydroascorbate reductase, glutathione reductase, and glutathione-S-transferase, exhibit altered anti-oxidant metabolism and improved abiotic stress tolerance
