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Transcriptional regulation of nf-e2 p45-related factor (NRF2) expression by the aryl hydrocarbon receptor-xenobiotic response element signaling pathway: DIRECT CROSS-TALK BETWEEN PHASE I AND II DRUG-METABOLIZING ENZYMES

doi:10.1007/s00424-015-1690-8 Nakajima, Kei et al

In addition to oxidative base modifications, ROS attack on DNA can result in the formation of DNA strand breaks (DSBs)

A new in vivo method to retard progression of intervertebral disc degeneration through stimulation of endogenous stem cells with simvastatin

[DOI] [PubMed] [Google Scholar] [243].Alli E, Ford JM

While we did not measure enzyme activity per se , these findings indicate that GSH synthesis and regeneration may be higher during the dark period