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For example, KO of nuclear receptor Rev-erb-, an activator of mitochondrial biogenesis and function, increases, rather than decreases, muscle BCAT2 mRNA levels (30%) (Marchesini et al., 2003)

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doi: 10.1016/j.foodchem.2003.09.023

Gonzlez Olmo BM, Butler MJ, Barrientos RM (2021) Evolution of the Human Diet and its impact on Gut Microbiota, Immune responses, and Brain Health
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