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The antioxidant role of luteolin in mice with pulmonary embolism is in line with its inhibition of ROS production from human platelets stimulated with collagen and convulxin (Figure 2)

Free iron is reactive and dangerous to cells, and NRF2 regulates the expression of ferritin heavy and light chains (FTL and FTH1), which immediately bind free iron, as well as ferroportin, which exports it [79]

Effect of prolonged exercise and carbohydrate ingestion on type 1 and type 2 T lymphocyte distribution and intracellular cytokine production in humans

doi: 10.1098/rstb.2010.0228

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Targeting the SOX4/EZH2/SLC7A11 pathway can be a novel therapeutic strategy to prevent CaOx crystal deposition-induced kidney injury