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Urinary excretion of l-carnitine and acylcarnitines by patients with disorders of organic acid metabolism: evidence for secondary insufficiency of l-carnitine

Blood 112, 935945 (2008)

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Can I use oral B vitamins and amino acid supplements instead of injections? Oral forms provide similar nutrients but with significantly lower bioavailability methylcobalamin absorption via oral route is approximately 12% compared to 9095% via injection, and first-pass hepatic metabolism reduces amino acid bioavailability by 3050% when taken orally

122 Thus, prolonging therapy can be considered in patients who are slow to respond (clearance of HCV RNA between weeks 12 and 24)