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This resulted in chimeric mAbs of approximately 65% human origin by amino acid content ( Chimeric mAbs exhibited an extended half-life and reduced immunogenicity, but they still presented a considerably high propensity for ADA induction ( H and V L , respectively), for mAbs that are approximately 95% human ( Technological advances of phage display technology ( While both humanized and fully human mAbs reduce immunogenic potential and show properties similar to human endogenous IgGs, they fail to completely eliminate mAb immunogenicity and ADA formation (Table 1 summarizes mAbs that are currently approved in the US and EU, along with their reported immunogenicity rates

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Environ Sci Technol 58:795804

A-Molecular Phylogenetic analysis using the Maximum Likelihood method

Processing of natural sounds in human auditory cortex: tonotopy, spectral tuning, and relation to voice sensitivity

The mice were treated by the protocol of the Institute Animal Care and Use Committee of Gyeongsang National University (approval No