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Humphrey LL, Fu R, Rogers K, Freeman M, Helfand M

Immunogenicity: No Antibody Formation A critical safety consideration for any peptide therapy is immunogenicity, the potential to trigger immune system responses that could lead to allergic reactions, reduced efficacy through antibody neutralization, or autoimmune complications

Biochemistry 41 , 84558463 (2002)

Dark spots start fading off and ultimately resorb to the normal skin color

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