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This decline correlates with visible aging signs, reduced wound healing capacity, and decreased tissue regeneration, providing the rationale for supplementation

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doi: 10.1371/journal.pmed.0030091

Global Grk4 knockout mice have lower SBP and DBP than Grk4 wild-type (WT) mice [78]

Fat and Liver Health: MOTS-c prevents diet-induced obesity and insulin resistance, reduces hepatic fat accumulation, and shows potential for treating MASLD (Metabolic Dysfunction Associated Steatotic Liver Disease)