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10.1016/j.cell.2012.03.042 37 Dos ReisL

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PKR promotes intestinal epithelial cell homeostasis and survival by activating the eIF2-mediated UPR, as well as the STAT3 and AKT signaling pathways

Metabolic and glucose regulation : Berberine has been studied for its effects on blood glucose control, with some research suggesting it may improve insulin sensitivity and reduce fasting blood glucose levels through AMPK activation

Carnitine regulatory abnormalities have been attributed to diabetic complications, trauma, hemodialysis, starvation, obesity, cardiomyopathy, fasting, endocrine imbalances, medication interactions, and other conditions (Guerra et al., 2021)